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Research Studies

Primary care research explores diseases and treatments that are important and relevant to patients. Evidence based practice plays a vital role in delivering best clinical and holistic care.

We are RCGP accredited “Research Ready” organisation and delighted to be working with National Institute of Health Research (NIHR) Clinical Research Networks (CRN).

We are actively recruiting patients for the studies below.

Current Studies – Active Recruitment

East London Genes and Health

South Asian people have some of the highest rates of heart disease, diabetes, and poor health in the UK. Living with a long term illness has a major impact on a person’s quality of life and on their family.

East London Genes and Health is a medical research study set up to help fight against these and other major diseases.

The primary objective of the research is to investigate and understand why some individuals have a disease, and help suggest how new medicines and treatments might be developed.

 

PAM study

Acronym. Programme on Adherence to Medication

In England, there are 13.5 million adults diagnosed with Hypertension and more than 5.5 million are undiagnosed. Hypertension(High Blood Pressure; HBP) accounts for 75,000 deaths, and is often accompanied with diabetes type 2 (DT2), cholesterol, and other health problems.

Hypertension is a major risk factor for disability and premature deaths, and medication adherence can considerably lower these risks.

The primary objective of the research is to assess the feasibility of face to face and digital intervention to support adherence to anti-hypertensive medications and improve blood pressure in primary care.

 

ATTACK

Acronym. Aspirin To Target Arterial Chronic Kidney Disease

In patients with cardiovascular disease (CVD), there is good evidence that antiplatelet therapy reduces the risk of subsequent vascular events (secondary prevention), and that overall these benefits outweigh the risks of major bleeding, which is the principle complication of therapy.

There is currently insufficient evidence to recommend the use of aspirin for the primary prevention of CVD in chronic Kidney Disease (CKD).

The primary objective of the research is to test the hypothesis that low-dose (75mg non-enteric coated) aspirin reduces the risk of major vascular events (excluding confirmed intracranial haemorrhage) (primary endpoint) in people with CKD who do not have pre-existing CVD.

 

GLAD

Acronym. Genetic Link to Anxiety and Depression

The study investigates both physical and mental health, with a particular focus on psychological and biological (genetic) risk factors associated with anxiety and depression.

The primary objective of the research is to develop better treatments by exploring genetic and environmental factors associated with risk of the disorders.

 

MAGNIFY

Acronym. Maximising Adherence and Gaining New Information for Your COPD

This will be the first ever cluster randomised study in the UK to evaluate the impact of a dual bronchodilator inhaler and adherence technology device with mobile app on clinical outcomes in COPD patients with frequent exacerbations.

The primary objective of the research is to evaluate the impact of an enhanced adherence package (dual bronchodilator inhaler + adherence technology device with mobile app) on time to treatment failure and other clinical outcomes in exacerbating COPD patients over one year.

 

Previous Studies – No Active Recruitment

CLASP5

ARRISA

iQuit

PACT

qFIT


 If you are interested in any of the studies or would like more information, please contact our research team on 01923 202 600

Dr Alex Carefull

Dr Ariff Amin

Rezwona Chowdhury - Research Nurse

Paula Hankin - Research Co-ordinator

Lisa Mackin - Practice Manager

Elizabeth Thomson- Reception Team Leader

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